Why NAD+ Supplements Should be Offered in Addition to GLP-1 Medications

Nicotinamide adenine dinucleotide, or NAD+, is a coenzyme found in all living organisms. It can be used as an effective supplement to GLP-1 medications by aiding in weight loss, promoting cellular energy, and helping to reduce the effects of aging.

GLP-1 medications have risen substantially in popularity in recent years. They are offered by a majority of weight loss clinics across the country. NAD+ supplementation, when combined with GLP-1 medications, can produce a synergistic effect that helps aid in patient outcomes and can provide weight loss clinics with additional sources of revenue. With the Business Biohacking Blueprint, we help established businesses optimize their weight loss treatments as well as help find new ways to increase revenue with innovative treatments, and we highly recommend that any clinic offering GLP-1 medications should look to incorporate the usage of NAD+ supplements.

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About GLP-1 Medications

Created to help treat type 2 diabetes, GLP-1 medications such as semaglutide and tirzepatide are now being used to help patients with weight loss. These medications are now offered by weight loss clinics across the world because of their proven results in helping patients lose weight. GLP-1 medications work by mimicking the hormone GLP-1 in the body which ultimately regulates blood sugar and helps create feelings of satiety. While GLP-1 medications are known as an effective method for weight loss, they do come with a variety of noteworthy side effects. Patients who take GLP-1 medications might experience a decrease in metabolism and overall energy as they begin to lose body fat.

About NAD+

NAD+ is a vital coenzyme found in every living cell and is largely responsible for the creation of cellular energy. This molecule facilitates critical biological processes, including the conversion of food into energy, DNA repair, and cell signaling. NAD+ is a centerpiece of metabolic function. As we age, levels of NAD+ naturally decline, leading to diminished cellular function and an increased risk of diseases. Research highlights that reduced NAD+ levels contribute to metabolic dysfunction and fatigue, and that supplementation of NAD+ can help counteract some of these effects. (1) Because of NAD+’s importance regarding cellular function, it is often used as a supplement by people looking to improve overall health.

Types of NAD+ Treatments

There are several different ways that NAD+ can be administered. The two most common methods are utilizing intravenous injections(IV) and through self-injection similar to how patients administer GLP-1 medications. Each method offers its own set of advantages. NAD+ treatments administered through IV drips allow for full absorption of NAD+ into the bloodstream, where it is ready for usage immediately. From a patient’s perspective, however, this would require them to travel to your business to receive treatments which might not be appealing to all. At-home injections, on the other hand, can be an easy addition to a patient’s already established GLP-1 administration routine.

Benefits of NAD+ Treatments

NAD+ treatments offer patients a wide variety of potential benefits, especially when combined with GLP-1 medications. Because NAD+ is present in nearly every living cell, supplementing with NAD+ can provide countless benefits. Some of these benefits may include, but are not limited to, the following:

There is no shortage of potential benefits associated with NAD+ treatments. On their own, NAD+ treatments can be a great addition to the treatments you offer with your business. With this in mind, NAD+ supplements can be extra beneficial to people taking GLP-1 medications, and they can be an effective pairing to market to patients.

Why Offer NAD+ in Addition to Your GLP-1 Treatments?

NAD+ treatments on their own can be a fantastic new asset to your treatment offerings. The benefits of NAD+ treatments ultimately speak for themselves, similarly to how the benefits of GLP-1 medications help market the treatment on their own. It is important to note, however, that NAD+ and GLP-1 work very well to achieve a variety of functions, and incorporating the two of them together into your practice can help these two treatments promote each other. The main reason why NAD+ supplements make for a great addition to GLP-1 medications is because of their ability to help mitigate the side effects of GLP-1.

Patients taking GLP-1 medications are likely to lose weight which can have many obvious health benefits, however, this is oftentimes not without its fair share of side effects, which can become severe enough for some patients that they will opt to discontinue usage of the medication. The benefits of NAD+ can help combat some of these side effects, which is a potential major selling point for patients considering beginning the usage of GLP-1 medications but are wary of the side effects. Here are some of the ways NAD+ interacts with GLP-1 in a positive way that can be both beneficial and marketable to your patients:

Increased Cellular Energy

One of the common side effects of significant weight loss is a lack of energy. People on GLP-1 medications often might find themselves eating less food because these medications are known to decrease appetite. As such, there is simply less food in their system to be used for energy. In addition to this, GLP-1 medications work largely by slowing down the digestive system, and this can make it difficult for the food that people taking GLP-1 medications eat to be converted into cellular energy. NAD+ works directly to help convert food into energy on a cellular level, therefore combatting the lack of energy associated with weight loss on GLP-1 medications.

Increased Metabolism

As one begins to lose weight, their metabolism tends to slow down as their body starts to adjust to its new form. This is especially true for patients who take GLP-1 medications and have lost a significant amount of weight. NAD+ is crucial for regulating metabolic pathways and can help patients with their metabolic function after losing weight on GLP-1 medications, especially in those who have low levels of NAD+, to begin with. (2)

Patients taking GLP-1 medications might become discouraged as they begin to run into somewhat of a weight loss plateau due to a slowing metabolism, especially if they are experiencing other side effects from GLP-1 medications as well. Adding NAD+ in addition to your GLP-1 treatments can be a great way to help patients who have surpassed the excitement of the initial weight loss phase and are considering going off of GLP-1 medications due to other side effects.

Increased Recovery from Activity

Although it is not always the case, many people taking GLP-1 medications might find themselves starting to become more active as they begin to lose weight and develop overall healthier lifestyles. One of the hardest parts of adopting a new exercise routine is that your body is often not used to the physical stress it is undergoing, leading to longer recovery times during the initial phases of developing a more active lifestyle. NAD+ medications are shown to help with muscle repair and recovery from physical activity. (2) Taking NAD+ therefore can make it easier for individuals taking GLP-1 medications to continue on their path to living a healthy, active life.

Decreased Brain Fog

Weight loss is commonly associated with brain fog due to a variety of reasons. Patients taking GLP-1 medications might find themselves experiencing a mild sense of cognitive decline as they begin to lose weight. NAD+ supplementation is known to help with overall brain function, as it is associated with synaptic plasticity and neuronal resistance. (3) Patients taking NAD+ supplements might notice an increase in overall cognitive function, especially in those who are short in NAD+.

How to Start Offering NAD+ Treatments with GLP-1

The Business Biohacking Blueprint has all the tools you need to help boost your business. We have helped thousands of clients with our weight loss treatments and hundreds of clinics leverage reach a greater audience and boost productivity. Adding NAD+ treatments to the services you offer will greatly help promote your existing GLP-1 offerings, and we can help you get started in doing so.

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References

1. Taichi Nagahisa, Shotaro Kosugi, Yamaguchi S. Interactions between Intestinal Homeostasis and NAD+ Biology in Regulating Incretin Production and Postprandial Glucose Metabolism. Nutrients. 2023;15(6):1494-1494. doi:https://doi.org/10.3390/nu15061494
2. Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. Nature Reviews Molecular Cell Biology. 2020;22(2):119-141. doi:https://doi.org/10.1038/s41580-020-00313-x
3. Lautrup S, Sinclair DA, Mattson MP, Fang EF. NAD+ in Brain Aging and Neurodegenerative Disorders. Cell Metabolism. 2019;30(4):630-655. doi:https://doi.org/10.1016/j.cmet.2019.09.001